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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Pharmacol Ther. 2012 Jul 10;136(1):8–22. doi: 10.1016/j.pharmthera.2012.07.001

Figure 3. Diagram of recombinant tau constructs.

Figure 3

(A) Construct K19 consisting of only three repeats in the Repeat Regions (RR) from residue 244–372 missing residues 308–326 corresponding to RR2/E10. (B) Construct K18 consisting of four repeats in the RR from residues 244–372. The hexapeptide motifs PHF6 (VQIVYK) and PHF6* (VQIINK) that promote the assembly of β structure are highlighted in yellow in both constructs.