Fig 5.
The congenic strains XL280α and XL280a have equal virulence to each other and the parental XL280p strain individually or coinfected. (A) Mice were inoculated with 1 × 106 fungal cells intranasally, and their survival was monitored for 40 days. There was no difference observed in survival rates among the strains. The P values were 0.833 (XL280p/XL280α), 0.252 (XL280p/XL280a), 0.984 (XL280p/a + α), 0.075 (XL280α/XL280a), 0.754 (XL280α/a + α), and 0.053 (XL280a/a + α). (B) Mice were inoculated with 1 × 106 fungal cells intravenously, and there was no difference among these strains. The P values were 0.317 (XL280p/XL280α), 0.317 (XL280p/XL280a), 1 (XL280p/a + α), 1 (XL280α/XL280a), 0.317 (XL280α/a + α), and 0.317 (XL280a/a + α).