Fig 3.

(A) Increase in PGE₂ release from T. cruzi-infected (MOI, 0.2) mouse cardiac myocytes with or without pretreatment with (R)- or (S)-BEL (2 μM; 10 min). **, P < 0.01 compared to unstimulated release. and ++, P < 0.01 when comparing results for T. cruzi-infected myocytes in the presence or absence of (R)-BEL. The values shown are means ± SEM for 6 separate cell cultures. (B) Increase in PGE₂ release from thrombin-stimulated (0.1 IU/ml) mouse cardiac myocytes with or without pretreatment with (R)- or (S)-BEL (2 μM; 10 min). **, P < 0.01 compared to unstimulated release, and ++, P < 0.01 when comparing results for thrombin-stimulated myocytes in the presence or absence of (R)-BEL. The values shown are means ± SEM for 6 separate cell cultures.