Table 4.
Antimicrobial susceptibility by collection source for Gram-positive isolates collected from pediatric patients as part of TEST 2004–2011a
| Species and collection source | n | % susceptible to drug: |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMOX-CLAV | Ampicillin | Ceftriaxone | Imipenem (n) | Levofloxacin | Linezolid | Meropenem (n) | Minocycline | Penicillin | PIP-TAZ | Tigecycline | Vancomycin | ||
| S. aureus | 3,614 | ||||||||||||
| Bodily fluids | 599 | 70.1 | 10.7 | 67.6 | 94.8 (115) | 83.1 | 100 | 94.2 (484) | 97.8 | 8.8 | 77.8 | 100 | 100 |
| CVS | 583 | 82.2 | 12.7 | 79.6 | 92.7 (124) | 84.2 | 100 | 89.8 (459) | 98.6 | 11.1 | 84.2 | 100 | 100 |
| GU | 35 | 80.0 | 22.9 | 77.1 | — (10) | 74.3 | 100 | 80.0 (25) | 94.3 | 20.0 | 85.7 | 100 | 100 |
| HEENT | 521 | 87.3 | 14.4 | 85.4 | 98.3 (120) | 88.1 | 100 | 95.8 (401) | 98.1 | 12.9 | 91.7 | 100 | 100 |
| Instruments | 55 | 65.5 | 16.4 | 65.5 | — (9) | 63.6 | 100 | 73.9 (46) | 98.2 | 14.5 | 69.1 | 100 | 100 |
| Integument | 1,038 | 74.0 | 8.4 | 71.9 | 98.2 (275) | 85.1 | 100 | 94.2 (763) | 98.4 | 6.6 | 79.0 | 100 | 100 |
| Reproductive system | 28 | 82.1 | 10.7 | 85.7 | — (9) | 89.3 | 100 | — (19) | 100 | 7.1 | 92.9 | 100 | 100 |
| Respiratory system | 690 | 83.9 | 13.2 | 81.0 | 93.7 (175) | 82.3 | 100 | 89.7 (515) | 99.1 | 11.6 | 86.7 | 100 | 100 |
| S. pneumoniae | 3,362 | ||||||||||||
| Bodily fluids | 214 | 91.1 | NA | 92.1 | 58.3 (36) | 99.5 | 100 | 79.2 (178) | 64.0 | 53.7 | NA | 98.6 | 100 |
| CNS | 25 | 100 | NA | 96.0 | — (7) | 100 | 100 | — (18) | 72.0 | 64.0 | NA | 96.0 | 100 |
| CVS | 664 | 91.6 | NA | 93.4 | 76.0 (146) | 99.5 | 100 | 80.3 (518) | 72.3 | 58.6 | NA | 99.1 | 100 |
| HEENT | 1,314 | 89.8 | NA | 93.6 | 72.8 (305) | 99.8 | 99.9 | 76.6 (1,009) | 68.9 | 55.2 | NA | 98.1 | 100 |
| Integument | 48 | 91.7 | NA | 93.8 | — (14) | 100 | 100 | 79.4 (34) | 66.7 | 58.3 | NA | 100 | 100 |
| Respiratory system | 1,049 | 85.0 | NA | 92.4 | 66.2 (272) | 99.5 | 100 | 69.1 (777) | 68.6 | 48.4 | NA | 98.6 | 100 |
| S. agalactiae | 1,056 | ||||||||||||
| Bodily fluids | 86 | NA | 100 | 100 | NA | 100 | 100 | 100 (73) | 11.6 | 100 | NA | 98.8 | 100 |
| CVS | 349 | NA | 100 | 100 | NA | 99.4 | 100 | 100 (287) | 10.0 | 100 | NA | 99.1 | 100 |
| GI | 21 | NA | 100 | 100 | NA | 100 | 100 | — (19) | 19.0 | 100 | NA | 100 | 100 |
| GU | 158 | NA | 100 | 100 | NA | 100 | 100 | 100 (112) | 15.8 | 100 | NA | 98.7 | 100 |
| HEENT | 148 | NA | 100 | 100 | NA | 100 | 100 | 100 (110) | 27.7 | 100 | NA | 99.3 | 100 |
| Integument | 108 | NA | 100 | 100 | NA | 99.1 | 100 | 100 (70) | 25.0 | 100 | NA | 100 | 100 |
| Reproductive system | 110 | NA | 100 | 100 | NA | 99.1 | 100 | 100 (82) | 14.5 | 100 | NA | 99.1 | 100 |
| Respiratory system | 63 | NA | 100 | 100 | NA | 100 | 100 | 100 (48) | 14.3 | 100 | NA | 100 | 100 |
| E. faecalis | 1,112 | ||||||||||||
| Bodily fluids | 124 | NA | 100 | NA | NA | 88.7 | 100 | NA | 38.7 | 100 | NA | 100 | 100 |
| CVS | 349 | NA | 99.7 | NA | NA | 89.1 | 100 | NA | 33.8 | 99.7 | NA | 99.4 | 99.4 |
| GU | 292 | NA | 99.7 | NA | NA | 87.7 | 99.7 | NA | 30.5 | 99.0 | NA | 99.3 | 99.7 |
| HEENT | 80 | NA | 98.8 | NA | NA | 86.3 | 100 | NA | 41.3 | 98.8 | NA | 100 | 98.8 |
| Instruments | 41 | NA | 100 | NA | NA | 85.4 | 100 | NA | 36.6 | 100 | NA | 100 | 100 |
| Integument | 131 | NA | 99.2 | NA | NA | 81.7 | 99.2 | NA | 33.6 | 99.2 | NA | 100 | 99.2 |
| Reproductive system | 24 | NA | 100 | NA | NA | 91.7 | 100 | NA | 20.8 | 100 | NA | 100 | 100 |
| Respiratory system | 45 | NA | 100 | NA | NA | 86.7 | 100 | NA | 35.6 | 100 | NA | 100 | 100 |
| E. faecium | 267 | ||||||||||||
| Bodily fluids | 31 | NA | 32.3 | NA | NA | 29.0 | 100 | NA | 64.5 | 22.6 | NA | 100 | 67.7 |
| CVS | 107 | NA | 33.6 | NA | NA | 36.4 | 98.1 | NA | 66.4 | 30.8 | NA | 100 | 71.0 |
| GU | 51 | NA | 11.8 | NA | NA | 29.4 | 100 | NA | 64.7 | 13.7 | NA | 100 | 82.4 |
| Integument | 29 | NA | 27.6 | NA | NA | 27.6 | 96.6 | NA | 65.5 | 24.1 | NA | 100 | 65.5 |
a
Abbreviations and symbols: CNS, central nervous system; CVS, cardiovascular system; GI, gastrointestinal; GU, genitourinary; HEENT, head, ears, eyes, nose, and throat; NA, susceptibility breakpoint not available; —, n is <20, and therefore, percent susceptible is not given.