Table 2.
Number tested and percentages of KPC-producing isolates according to susceptibility categories assigned using the current CLSI breakpoints
| Antimicrobial agent | No. tested (all species/K. pneumoniae only) |
Comparison of percentages by categorya (all species/K. pneumoniae only) |
||||
|---|---|---|---|---|---|---|
| Susceptible |
Resistant |
|||||
| 2000–2005 | 2006–2010 | 2000–2005 | 2006–2010 | 2000–2005 | 2006–2010 | |
| Aztreonam | 80/42 | 328/264 | 0.0/0.0 | 0.0/0.0 | 97.5/100.0 | 99.7/99.6 |
| Cefepime | 80/42 | 419/347 | 32.5/14.3 | 11.0/7.2 | 0.0/0.0 | 21.5/31.1 |
| Ceftazidime | 80/42 | 419/347 | 7.5/0.0 | 1.7/1.2 | 88.7/95.2 | 94.5/96.3 |
| Ceftriaxone | 80/42 | 419/347 | 0.0/0.0 | 0.2/0.3 | 100.0/100.0 | 99.8/99.7 |
| Ertapenem | 62/34 | 419/347 | 0.0/0.0 | 0.5/0.6 | 96.8/100.0 | 98.1/98.3 |
| Imipenem | 80/42 | 417/345 | 1.3/0.0 | 0.5/0.6 | 98.7/100.0 | 99.5/99.4 |
| Meropenem | 80/42 | 419/347 | 2.5/0.0 | 3.1/2.6 | 81.2/97.6 | 93.1/94.5 |
| Piperacillin-tazobactam | 80/42 | 419/347 | 0.0/0.0 | 0.7/0.9 | 91.2/100.0 | 97.1/97.7 |
a
Results in boldface were considered significant (P < 0.05); statistical significance of percentages between groups was assessed using the chi-square test.