Fig 1.

Determination of arginase I expression (left panel) and arginase activity (right panel) in sera from controls (n = 23) and patients with human African trypanosomiasis (n = 32) from the Couloir focus (Republic of Congo). ●, Controls; ◆, stage 1 patients; ■, stage 2 patients. Black lines represent the medians and quartiles for each group. The arginase activity was higher in HAT patients than in controls (median, 4.82 U/liter versus 2.65 U/liter, P < 0.001). Serum arginase I expression was higher in HAT patients than in controls (median, 37 ng/ml versus 17 ng/ml, P < 0.001).