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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Psychopharmacology (Berl). 2012 Aug 19;225(2):473–482. doi: 10.1007/s00213-012-2837-3

Figure 5.

Figure 5

The effects of vehicle administration on cue-induced reinstatement of nicotine seeking over time and with repeated cue-induced reinstatement testing (n = 21/dose). AL=active lever presses. V1= first reinstatement session conducted immediately after the 10 day extinction phase; V2 = reinstatement session after vehicle administration conducted as part of a within-subjects Latin-square design; V3 = reinstatement session after vehicle administration conducted after completing the Latin-square design. Pound signs (##p < 0.01, ###p < 0.001) indicate difference from extinction.