Brain volumes at hospital discharge and at three-month follow-up ^a

Anatomical Region	Hospital Discharge Brain volumes for the entire cohort (N=47)	Three-month Follow-up Brain volumes for the entire cohort (N=47)	Hospital Discharge Brain volumes for patients scanned at discharge and at three-month follow-up (N=36)	Three-month Follow-up Brain volumes for patients scanned at discharge and at three-month follow-up (N=36)
VBR	3.5 (2.4, 5.3); 4±1.9	3.8 (2.2, 5.0); 3.8±1.7	3.4 (2.2, 5.3); 3.9±1.8	3.8 (2.2, 5.0); 3.8±1.7
Gray Matter, cm3	366 (346, 394); 373±45	348 (375, 403); 381±50	365 (347, 394); 374±46	375 (348, 403); 381±50
White Matter, cm3	496 (457, 521); 496±66	483 (−443, 524); 489±70	488 (455, 521); 494±70	483 (443, 524); 484±70
Hippocampus, cm3	6.4 (6.04, 6.68); 6.2±0.97	6.4 (5.9, 6.8); 6.2±1.1	6.5 (6.0, 6.7); 6.1±1.1	6.4 (5.9, 6.8); 6.2±1.1
Superior Frontal Lobe, cm3	31.8 (29.7, 34.5); 32.5±4.8	33 (30, 35); 33±5	31.9 (29.8, 34.4); 32.4±4.8	33 (30, 35); 33±5
Frontal Lobe, cm3	133 (123, 139); 134±18	133 (121, 144); 133±27	134 (120, 139); 134±19	133 (121, 144); 133±27
Thalamus, cm3	11.5 (10.7, 12.4); 11.7±1.7	11.6 (10.7, 12.7); 11.7±1.7	11.5 (10.6, 12.4); 11.6±1.5	11.6 (10.7, 12.7); 11.7±1.7
Precuneus, cm3	15.2 (14.2, 16.3); 15.4±2.4	15.8 (14.4, 17.0); 15.9±2.4	15.4 (14.2, 16.3); 15.6±2.1	15.8 (14.4, 17.0); 15.9±2.4
rACC, cm3	3.2 (2.89, 3.54); 3.3±0.6	3.16 (2.89, 3.42); 3.2±0.6	3.2 (2.91, 3.54); 3.3±0.5	3.2 (2.89, 3.42); 3.2±0.6
Cerebellum, cm3	104 (96, 113); 105±13	104 (96, 113); 106±15	105 (94, 114); 105±14	104 (96, 113); 106±15

^aAll results expressed as median (interquartile range) and mean ± SD.

Abbreviations: CI, confidence interval; VBR, ventricle-to-brain ratio; rACC, rostral anterior cingulate cortex

Abbreviations: CI, confidence interval; VBR, ventricle-to-brain ratio; rACC, rostral anterior cingulate cortex