Table 4: ICER of TAVI Versus ST in 3-Way Sensitivity Analysesa.
|
Increment in Utility (TAVI Versus ST) |
Difference in Total Cost of TAVI Versus ST | |||
|---|---|---|---|---|
|
$15,233 (Base Case) |
$25,233 | $35,233 | $45,233 | |
| Life Table Mortality After 1 Year for Both TAVI and ST (Base Case) | ||||
| 0 | $37,163 | $61,560 | $85,957 | $110,354 |
| 0.04 | $29,354 | $48,625 | $67,895 | $87,166 |
| 0.08 (base case) | $24,257 | $40,182 | $56,106 | $72,030 |
| 0.12 | $20,669 | $34,237 | $47,805 | $61,373 |
| Mortality After 1 Year of 0.50 for Both ST and TAVI | ||||
| 0 | $68,466 | $134,625 | $200,783 | $266,942 |
| 0.04 | $47,389 | $93,181 | $138,973 | $184,765 |
| 0.08 | $36,234 | $71,248 | $106,261 | $141,274 |
| 0.12 | $29,330 | $57,672 | $86,014 | $114,356 |
| Mortality After 1 Year of 0.50 for ST and 0.30 for TAVI | ||||
| 0 | $30,874 | $52,568 | $74,263 | $95,957 |
| 0.04 | $26,323 | $44,820 | $63,317 | $81,814 |
| 0.08 | $22,942 | $39,063 | $55,183 | $71,304 |
| 0.12 | $20,330 | $34,616 | $48,901 | $63,187 |
Abbreviations: ICER, incremental cost-effectiveness ratio; ST, standard treatment; TAVI, transcatheter aortic valve implantation.
a
All amounts are in Canadian dollars.