Table 1.

Summary Statistics of Sequence Diversity in Africans, Europeans, and East Asians.

	Africans					Europeans					East Asians
Genes (length of sequences)	S (Spop)a	πb	TDc	FLDd	FLFe	S (Spop)	π	TD	FLD	FLF	S (Spop)	π	TD	FLD	FLF
NOD2 (3,016 bp)
Exon 4 (1,021 bp)	4 (2)	0.390	−0.585	0.842	0.429	4 (2)	0.880	0.849	0.820	0.996	1 (0)	0.022	0.291	0.457	0.477
Intron 7 to exon 9 (1,642 bp)	9 (4)	0.580	−0.665	1.231	0.644	11 (8)	0.720	−0.589	−2.770**	−2.354*	4 (1)	0.290	−0.548	0.893	0.492
Intron 10 to intron 11 (353 bp)	0 (0)	N.A.f	N.A.	N.A.	N.A.	1 (1)g	0.004	0.791	0.415	0.036	0 (0)	N.A.	N.A.	N.A.	N.A.
10q21 (513 bp)	4 (4)	0.130	−1.456*	−0.525	−1.006	2 (2)	0.050	−1.089	−1.407	−1.557	1 (1)	0.040	−0.897	0.456	0.046
IL23R (640 bp)	4 (1)	0.390	−0.984	−0.524	−0.813	3 (0)	0.520	−0.354	0.713	0.426	0 (0)	N.A.	N.A.	N.A.	N.A.

^aTotal number of segregating sites (that of segregating sites specific to a population).

^bNucleotide diversity in a population (×10⁻³).

^cTD, Tajima's D.

^dFLD, Fu and Li's D.

^eFLF, Fu and Li's F.

^fN.A. means that summary statistics were not calculated because there was no polymorphism in a population.

^gThe CD allele (frameshift mutation; SNP#35) specific to Europeans is not included in this analysis.

*P < 0.05, **P < 0.01: the significance of observed values estimated by coalescent simulation (1,000) assuming constant population size.