Skip to main content
. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Trends Genet. 2009 Oct 6;25(10):434–440. doi: 10.1016/j.tig.2009.08.003

Figure 1. Information theory as applied to DNA-binding motifs.

Figure 1

(a) The concepts of minimal information required in theory and in DNA recognition and the consequences of information deficiency, which results in spurious hits. (b) The sequence logos for low- and high- information motifs, and the likelihood of a spurious hit to the motif in a ‘random’ genomic background.