Table 1.
Statistical analysis of immunohistochemistry on treated tumor tissues
| Control(n = 5 mice) | IL-24(n = 5 mice) | IFN-α(n = 5 mice) | IL-24 and IFN-α(n = 5 mice) | P-value | |
|---|---|---|---|---|---|
| MMP |
74.0 ± 8.5 |
66.2 ± 10.2 |
48.0 ± 10.3* |
2.0 ± 1.9*†‡ |
<0.001 |
| OPN |
68.0 ± 12.8 |
0.6 ± 0.9* |
9.2 ± 3.7*† |
0.6 ± 0.5*‡ |
<0.001 |
| VEGF |
17.8 ± 4.7 |
1.6 ± 1.1* |
1.4 ± 1.5* |
0.8 ± 1.1* |
<0.001 |
| XIAP | 90.8 ± 3.6 | 0.8 ± 0.4* | 79.0 ± 7.0† | 0.6 ± 0.5*‡ | <0.001 |
* significant difference compared to the control group,
† significant difference compared to the IL-24 group.
‡ significant difference compared to the IFN-α group.