Table 2.
Complement components in multiple sclerosis disease subgroups and controls.
| No. | FB mg/l |
C3 mg/l |
C1s mg/l |
C4 mg/l |
C9 mg/l |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | p | Mean | SD | Mean | SD | p | Mean | SD | p | p* | ||
| Control | 35 | 194.02 | 68.28 | 1263.14 | 268.38 | N/A | 97.91 | 44.75 | 187.43 | 57.09 | N/A | 98.22 | 23.26 | N/A | <0.001 |
| Total MS | 176 | 183.98 | 53.52 | 1454.40 | 350.18 | 0.003 | 104.66 | 46.65 | 236.56 | 84.63 | 0.001 | 73.31 | 18.82 | <0.001 | N/A |
| S-RRMS | 37 | 171.97 | 35.25 | 1440.41 | 363.56 | 0.266 | 99.89 | 50.19 | 223.83 | 68.43 | 0.571 | 68.49 | 13.74 | <0.001 | 0.102 |
| A-RRMS | 68 | 199.10 | 69.27 | 1397.68 | 326.42 | 0.561 | 102.72 | 48.09 | 228.03 | 66.61 | 0.153 | 78.73 | 22.51 | <0.001 | N/A |
| SPMS | 34 | 173.31 | 33.74 | 1539.21 | 304.96 | 0.008 | 119.01 | 48.99 | 263.06 | 103.16 | 0.001 | 70.45 | 14.47 | <0.001 | 0.426 |
| PPMS | 37 | 177.99 | 44.54 | 1499.58 | 413.23 | 0.042 | 99.79 | 36.15 | 249.00 | 145.97 | 0.263 | 70.81 | 17.44 | <0.001 | 0.463 |
SD, standard deviation. p-values are measured using students t-test to compare MS and controls and ANOVA for multiple comparisons. p-values are shown for the subgroup analysis if a significant difference was seen at ANOVA. p = comparison with control group. p* = comparison with A-RRMS group. S-RRMS, stable relapsing–remitting MS with no relapses reported for at least 12 months; A-RRMS, acute relapsing–remitting MS sampled in relapse; SPMS, secondary progressive MS; PPMS, primary progressive MS.