Table 8.

Correlation of cerebrospinal fluid:plasma complement quotient with IgG index and albumin quotient.

		Correlation		Normal		Raised
		r	p	Mean CSF level	SD	Mean CSF level	SD	p
FB	IgG Index	0.41	0.001	0.74	0.41	0.92	0.33	0.056
	Albumin ratio	0.38	0.004	0.79	0.39	0.96	0.31	0.173
C9	IgG Index	0.46	<0.001	0.21	0.11	0.31	0.18	0.010
	Albumin ratio	0.65	<0.001	0.23	0.11	0.42	0.22	0.013
C1s	IgG Index	0.11	0.423	1.69	0.59	1.82	0.75	0.468
	Albumin ratio	0.35	0.011	1.67	0.66	2.16	0.57	0.024
Clusterin	IgG Index	0.22	0.110	1.57	0.95	1.86	0.75	0.175
	Albumin ratio	0.36	0.007	1.58	0.83	2.28	0.82	0.011
Factor I	IgG Index	0.02	0.860	0.16	0.11	0.19	0.12	0.375
	Albumin ratio	0.03	0.850	0.17	0.11	0.19	0.13	0.674
TCC	IgG Index	0.19	0.210	10.61	13.22	14.95	19.85	0.385
	Albumin ratio	–0.11	0.482	12.96	14.13	10.60	25.81	0.717

Correlations are shown between cerebrospinal fluid (CSF):plasma complement ratio and either the IgG index or CSF:serum albumin ratio (expect for TCC where plasma levels were not detectable and correlation is shown with CSF TCC). Normal and raised refer IgG index or CSF:serum albumin ratio in reference to their normal laboratory values; a raised value indicates either intrathecal IgG synthesis (raised IgG index) or breakdown of the blood–CSF barrier (raised CSF:serum albumin ratio). The p-value refers to the difference between mean CSF complement levels when the IgG index or CSF:serum albumin ratio is normal or raised. FB, factor B; FI, factor I; TCC, terminal complement complex.