Table 4. Power with pooling and errors, on 1000 data sets and a region with 100 rare SNVs.
Error rate | Pool size | Coverage per person | VST | LRT |
---|---|---|---|---|
0 | 1 | 4 | 0.973 | 0.975 |
10 | 0.98 | 0.99 | ||
20 | 0.987 | 0.988 | ||
5 | 4 | 0.977 | 0.981 | |
10 | 0.98 | 0.989 | ||
20 | 0.982 | 0.988 | ||
0.01 | 1 | 4 | 0.634 | 0.745 |
10 | 0.965 | 0.972 | ||
20 | 0.988 | 0.993 | ||
5 | 4 | 0.376 | 0.557 | |
10 | 0.85 | 0.924 | ||
20 | 0.981 | 0.987 |
PAR of the region was 0.02, with ci = 0.1 and a significance threshold of 0.05.