Table 3.
Specificity and sensitivity (%) of HBV and HCV immunoassay outcome prediction after decision tree ensemble analyses
| (a) Measure | Raw | Scale | Log | Scale-log |
|---|---|---|---|---|
| HBSA specificity |
53.91 |
54.46 |
54.41 |
54.41 |
| HBSA sensitivity |
62.22 |
59.82 |
59.82 |
59.82 |
| HepC specificity |
57.75 |
57.65 |
57.77 |
57.66 |
| HepC sensitivity |
63.19 |
63.45 |
63.08 |
63.31 |
|
(b) Measure |
Raw |
Scale |
Log |
Scale-log |
| HBSA specificity |
68.57 |
68.82 |
68.80 |
68.57 |
| HBSA sensitivity |
46.83 |
46.91 |
46.83 |
46.83 |
| HepC specificity |
58.87 |
58.91 |
58.88 |
58.87 |
| HepC sensitivity |
63.40 |
63.34 |
63.34 |
63.37 |
|
(c) Measure |
Raw |
Scale |
Log |
Scale-log |
| HBSA specificity |
54.45 |
54.59 |
45.74 |
45.74 |
| HBSA sensitivity |
61.43 |
61.43 |
70.20 |
70.20 |
| HepC specificity |
35.04 |
34.87 |
36.90 |
36.88 |
| HepC sensitivity | 80.37 | 80.84 | 76.53 | 76.53 |
Methods employed were (a) basic multiple, (b) majority multiple and (c) clear negative analyses (see Methods). Prior to accuracy analysis, explanatory variables were subject to one of four pre-processing methods: none (raw), scaling, logging and scale-logging. Scaling sets the range of each explanatory variable to a common range of 0 – 100. Logging uses natural logarithm transformation. Scale-logging uses a common range of 0 – 100 then takes the natural logarithm.