Table 1.

Non-conservative amino acid exchanges (Dayhoff matrix index < 5) in selected proteins* of clone CHA strains

Locus_tag	Name	Encoded product	aa exchange
PA0247	PobA	p-hydroxybenzoate hydroxylase	T98M
PA0595	OstA	organic solvent tolerance protein precursor involved in outer membrane biogenesis	M907T
PA0831	OruR	transcriptional regulator of ornithine utilization	W197C
PA1148	ToxA	exotoxin A precursor	F22S
PA1712	ExsB	exoenzyme S synthesis protein B	R52G
PA1717	PscD	type III secretion export protein	V346E
PA1718	PscE	type III secretion export protein	C40G
PA2236	PslF	glycosyl transferase, Psl exopolysaccharide biosynthesis	Y247D
PA3061	PelD	membrane-bound c-di-GMP-specific receptorregulating Pel exopolysaccharide production	Y208H
PA3063	PelB	Pel exopolysaccharide biosynthesis	W791L
PA3344	RecQ	ATP dependent DNA helicase	R571C
PA3805	PilF	pilus biogenesis, outer membrane pilotin for localization and multimerization of secretin PilQ	L243P
PA3810	HscA	molecular chaperone	R285G
PA3910	EddA	extracellular DNA degradation protein	P368L
PA3946	RocS1	sensor of two-component system controlling cupC fimbrial and efflux pump gene expression	I399S
PA4085	CupB2	periplasmic chaperone	H242L
PA4086	CupB1	major pilus subunit	Q102T; V154E
PA4776	PmrA	two component regulatory system modulating resistance to cationic antimicrobial peptides	L71R
PA4777	PmrB	two component regulatory system modulating resistance to cationic antimicrobial peptides	Y345H
PA5483	AlgB	two component response regulator controlling alginate biosynthesis	L382R
PA5484	KinB	two component sensor kinase (negative regulation of alginate production, positive regulation of virulence-associated phenotypes)	Y50H
PA5493	PolA	DNA polymerase I	C882R

Exchanges are given in comparison to protein sequences from the PAO1 reference.

*The function of the encoded gene product has been experimentally demonstrated (annotation class I).