Table 2.
Results for S. cerevisiae
| A) S. cerevisiae Biological Process | |||||
|---|---|---|---|---|---|
| |
Degree |
Betweenness |
Transitivity |
Hubscore |
Closeness |
| GRN/PPN |
32/1265 |
0/1265 |
2/1265 |
0/1265 |
0/1265 |
| TRN/PPN |
0/1057 |
0/1057 |
0/1057 |
0/1057 |
0/1057 |
| GRN/TRN |
1/1044 |
0/1044 |
1/1044 |
0/1044 |
0/1044 |
|
B)S. cerevisiae Cellular Component | |||||
| GRN/PPN |
4/295 |
0/295 |
7/295 |
5/295 |
0/295 |
| TRN/PPN |
0/245 |
0/245 |
0/245 |
0/245 |
0/245 |
| GRN/TRN |
0/241 |
0/241 |
0/241 |
0/241 |
0/241 |
|
C)S. cerevisiae Molecular Function | |||||
| GRN/PPN |
0/375 |
0/375 |
5/375 |
3/375 |
0/375 |
| TRN/PPN |
2/308 |
0/308 |
0/308 |
0/308 |
0/308 |
| GRN/TRN |
0/304 |
0/304 |
0/304 |
0/304 |
0/304 |
|
D)S. cerevisiae transitivity centrality GRN/PPN (Cellular Component) | |||||
|
GO |
Term |
Size |
ρ |
pfdr |
|
| GO:0031597 |
Cytosolic proteasome complex |
202 |
0.30 |
0.002024 |
|
| GO:0005875 |
Microtubule associated complex |
560 |
0.16 |
0.009816 |
|
| GO:0019005 |
SCF ubiquitin ligase complex |
26 |
0.65 |
0.01706 |
|
| GO:0031903 |
Microbody membrane |
17 |
0.74 |
0.02134 |
|
| GO:0000785 |
Chromatin |
522 |
0.15 |
0.02134 |
|
| GO:0000313 |
Organellar ribosome |
17 |
0.74 |
0.02134 |
|
| GO:0005654 | Nucleoplasm | 12 | 0.81 | 0.03283 | |
Spearman’s rank correlation coefficient test for centrality measures between the GRN, TRN and PPN of Gene Ontology subnetworks for A Biological Process, B Cellular Component and C Molecular Function. A-C Tests are performed for degree, betweenness, transitivity (local clustering coefficient), hubscore and closeness centrality. Each column, shows the number of significant terms and the total number of terms tested. D shows 7 terms for cellular components with significant transitivity centrality between theS. cerevisiaeGRNand PPN.