Table 1.
Characteristics of 450 HIV-positive, hepatitis C virus-positive women in Women’s Interagency HIV Study on HAART at index visit.
| Characteristicsa | Died (N = 191) | Alive at last follow-up (N = 259) | Overall (N = 450) |
|---|---|---|---|
| Age (years) | 44 (40–48) | 43 (39–47) | 43 (40–47) |
| Race/ethnicity [% (n)] | |||
| Non-Hispanic white | 15 (28) | 17 (43) | 16 (71) |
| Non-Hispanic black | 63 (121) | 62 (160) | 62 (281) |
| Hispanic | 20 (39) | 20 (53) | 20 (92) |
| Other | 2 (3) | 1 (3) | 1 (6) |
| Pre-HAART HIV peak viral load (copies/ml) | 93 000 (23 000–300 000) | 47 000 (9900–140 000) | 62000 (13 000–210 000) |
| Pre-HAART nadir CD4 cell counts (cells/µl) | 160 (81–272) | 241 (138–345) | 205 (102–316) |
| Clinical AIDS pre-HAART initiation [% (n)] | 61 (116) | 42 (110) | 50 (226) |
| Pre-HAART ART use [% (n)] | 79 (151) | 66 (170) | 71 (321) |
| HIV viral load (copies/ml) | 2250 (81–34 000) | 173 (80–3600) | 570 (80–13 000) |
| CD4 cell counts (cells/µl) | 230 (128–375) | 351 (200–516) | 313 (169–469) |
| HCV-RNA, ×103 IU/ml at entry into WIHS | 2880 (926–4960) | 1760 (551–3760) | 2085 (645–4020) |
| HBsAg-positive, % (n) at entry into WIHS | 3 (5) | 2 (4) | 2 (9) |
| Current alcohol use [% (n)] | |||
| Abstinent | 60 (115) | 59 (152) | 59 (267) |
| Light (<3 drinks/week) | 15 (28) | 24 (63) | 20 (91) |
| Moderate (3–13 drinks/week) | 16 (31) | 11 (29) | 1% (60) |
| Heavy (>13 drinks/week) | 7 (13) | 4 (10) | 5 (23) |
| Current IVDU -[% (n)] | 12 (23) | 8 (20) | 10 (43) |
| BMI (kg/m2) | 25.3 (21.4–28.9) | 25.6 (23.4–29.7) | 25.4 (22.7–29.3) |
| Waist circumference (cm) | 81 (75–91) | 87 (80–97) | 86 (78–95) |
| Diabetes [% (n)] | 6 (11) | 4 (11) | 5 (22) |
| Chronic renal disease [% (n)] | 14 (26) | 3 (8) | 8 (34) |
| AST (IU/l) | 53 (34–84) | 42 (33–60) | 46 (33–68) |
| ALT (IU/l) | 35 (23–63) | 37 (26–62) | 36 (25–62) |
| Follow-up time (years) | 4.3 (1.8–7.4) | 8.5 (5.7–10.7) | 6.6 (3.2–9.8) |
ALT, alanine aminotransferase; ART, antiretroviral therapy; AST, aspartate aminotransferase; HBsAg, surface antigen; HCV, hepatitis C virus; IVDU, intravenous drug use; WIHS, Women’s Interagency HIV Study.
a
Median (interquartile range) unless otherwise noted. Values are for index visit unless otherwise indicated.
The following characteristics had missing data: pre-HAART HIV peak viral load, n = 2; pre-HAART nadir CD4, n = 1; HIV viral load at index visit, 0 = 20; CD4 cell count at index visit, n = 5; BMI, n = 13; waist, n = 291; current alcohol use, n = 9; and current IVDU, n = 8.