Table 1. Basal plasma electrolyte and hormones and basal cardiovascular and renal parameters in 5 year old sham and uninephrectomised (uni-x) sheep.

	Sham (N = 5)	Uni-x (N = 5)
Plasma
Sodium (mmol/l)	137±0.6	136±1.1
Hematocrit (%)	25.4±0.7	24.5±0.6
Renin activity (ng/ml/h)	1.4±0.6	0.6±0.2**
AngII (pg/ml)	22.6±7.2	12.3±1.2*
Cardiovascular
MAP (mm Hg)	82±1	93±1****
Heart rate (beats/min)	82±4	85±5
Renal
GFR (ml/min/gkw)	1.02±0.1	0.62±0.1***
RBF (ml/min/gkw)	10.1±0.8	5.3±0.5***
RVR (mm Hg/ml/min/gkw)	8.4±0.7	17.9±1.4****
Fitration fraction (%)	13.9±1.8	16.6±2.8
UFR (ml/min/gkw)	0.01±0.005	0.01±0.002
UNaV (umol/min/gkw)	2.0±0.5	1.2±0.2
FENa %	1.4±0.4	1.2±0.4

^*P<0.05,

^**P<0.01,

^***P<0.001,

^****P<0.0001.