Figure 2. HS-Csn8KO yields differential effects of on proteasome subcomplexes in mouse livers.
(A) Representative images of western blot analyses of the indicated subunits of the 19 and the 20S proteasome in the liver of 4-week-old mice. (B) Pooled densitometry data of the western blot analysis of Rpt5 as illustrated in panel A. (C, D) HS-Csn8KO resulted in the upregulation of three subunits of the 11S proteasome. β-Tubulin was probed as the loading control. AU denotes arbitrary unit. n=4 mice/group; #p<0.05, *p<0.01 vs. CTL; Student’s t-test.