Table 2. Offspring body weight at birth and weaning, and metabolic and hormonal parameters at weaning.
| C | Csup | R | Rsup | ||
|---|---|---|---|---|---|
| Birth weight (g) | |||||
| Males (n) | 6.5±0.1 (29)a | 6.3±0.05 (21)a,c | 6.9±0.06 (45)b | 6.1±0.07 (40)c | |
| Females (n) | 6.2±0.07 (40)a | 5.8±0.09 (22)b | 6.5±0.06 (35)a | 5.8±0.07 (49)b | |
| Weight at weaning (g) | |||||
| Males (n) | 46.8±1.1 (17)a | 40.5±1.6 (12)ab | 37.1±0.7 (20)b | 26.2±0.6 (24)c | |
| Females (n) | 46.6±0.8 (14)a | 39.8±1.7 (12)ab | 36.5±0.8 (19)b | 25.9±0.6 (24)c | |
| Glucose (g/l) – Day 21 | |||||
| Males (n) | 0.97±0.01 (8)a | 1.04±0.03 (6)ab | 0.96±0.02 (8)ab | 0.84±0.02 (8)b | |
| Females (n) | 1.04±0.02 (8)a | 1.23±0.03 (6)b | 1.17±0.06 (8)b | 1.02±0.02 (8)ab | |
| Triglycerides (g/l) – Day 21 | |||||
| Males (n) | 1.97±0.20 (8)a | 1.26±0.16 (6)b | 0.56±0.04 (8)c | 0.50±0.04 (8)c | |
| Females (n) | 2.08±0.25 (8)a | 1.16±0.22 (6)b | 0.65±0.07 (8)c | 0.51±0.04 (8)c | |
| Cholesterol (g/l) – Day 21 | |||||
| Males (n) | 2.15±0.18 (8)a | 1.80±0.13 (6)ab | 1.83±0.12 (8)ab | 1.77±0.07 (8)b | |
| Females (n) | 2.04±0.13 (8)a | 1.66±0.11 (6)a | 1.69±0.07 (8)a | 1.89±0.10 (8)a | |
| Insulin (ng/ml) – Day 21 | |||||
| Males (n) | 0.63±0.04 (8)a | 0.65±0.09 (6)a | 0.34±0.04 (8)b | 0.18±0.03 (8)b | |
| Females (n) | 0.69±0.12 (8)a | 0.70±0.07 (6)a | 0.44±0.05 (8)b | 0.24±0.02 (8)b | |
| Leptin (ng/ml) – Day 21 | |||||
| Males (n) | 3.26±0.33 (8)a | 1.85±0.24 (6)b | 4.16±0.49 (8)a | 1.23±0.17 (8)b | |
| Females (n) | 4.01±0.53 (8)a | 2.43±0.19 (6)b | 4.23±0.65 (8)a | 0.81±0.16 (8)c | |
| Dams (n) | 3.58±0.73 (5)a | 3.05±0.59 (3)a | 2.53±0.39 (5)ab | 1.20±0.00 (6)b | |
(Mean±SEM). a b c Groups that share the same superscript are not significantly different from each other (p<0.05, Kruskal-Wallis and Dunn’s post hoc test, independently for each gender).
C: Control, Csup: Control MD supplemented, R: Protein Restricted, Rsup: Protein Restricted MD supplemented