Table 1.
Association between relaxin-2 mRNA expression and clinicopathologic factors
| Clinicopathologic factor | Total |
Serum relaxin-2 |
|
Relaxin-2 mRNA expression |
||
|---|---|---|---|---|---|---|
| (mean ± SEM) (ng/mL) | P-Value | Low(n) | High(n) | P-Value | ||
|
Sex |
|
|
0.456 |
|
|
0.568 |
| Female |
20 |
88.24 ± 13.27 |
|
7 |
13 |
|
| Male |
16 |
91.58 ± 12.36 |
|
8 |
8 |
|
|
Age(Years) |
|
|
0.087 |
|
|
0.092 |
| <20 |
21 |
95.23 ± 14.16 |
|
6 |
15 |
|
| ≥20 |
15 |
83.62 ± 12.61 |
|
9 |
6 |
|
|
Tumor location |
|
|
0.562 |
|
|
0.67 |
| Extremity |
14 |
91.54 ± 15.13 |
|
6 |
8 |
|
| Axial |
22 |
89.67 ± 14.86 |
|
9 |
13 |
|
|
Histologic subtypes |
|
|
0.893 |
|
|
0.746 |
| Osteoblastic |
12 |
91.65 ± 13.02 |
|
5 |
7 |
|
| Chondroblastic |
10 |
90.54 ± 13.48 |
|
4 |
6 |
|
| Fibroblastic |
9 |
89.04 ± 14.23 |
|
3 |
6 |
|
| Telangiectactic |
5 |
91.86 ± 13.35 |
|
3 |
2 |
|
|
Clinical stage |
|
|
0.004 |
|
|
0.018 |
| I + II |
20 |
76. 4 ± 15.27 |
|
11 |
9 |
|
| III |
16 |
114.53 ± 17.26 |
|
4 |
12 |
|
|
Hematogenous metastasis |
|
|
0.001 |
|
|
0.002 |
| No |
15 |
70.53 ± 10.42 |
|
11 |
4 |
|
| Yes |
21 |
108.6 ± 14.87 |
|
4 |
17 |
|
|
Grade |
|
|
|
|
|
0.742 |
| High |
30 |
89.12 ± 13.90 |
0.642 |
11 |
19 |
|
| Moderate |
3 |
94.40 ± 12.16 |
|
2 |
1 |
|
| Low | 3 | 96.18 ± 12.45 | 2 | 1 | ||