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. 2013 Jul 1;8(7):e68115. doi: 10.1371/journal.pone.0068115

Figure 7. Comparison of cellular response and humoral response against HIV after immunized with recombinant mutants and VTKgpe.

Figure 7

Comparison of cellular and humoral responses after mice were immunized with VTKgpe, VTKgpe△C7L, VTKgpe△K1L and VTT△C7LK1L-gag. Mice were sacrificed one week post-infection, and splenocytes were harvested. (A) The gag specific IFN-γ secreting cells were quantified by ELISPOT assay. (B) The env specific IFN-γ secreting cells were quantified. (C) The gag specific IL-2 secreting cells were quantified. (D) The env specific IL-2 secreting cells were quantified. (E) Serum were harvested and tested for p55-specific antibody levels by ELISA assay. (F) Serum was tested for gp120-specific antibody levels.