Table 1. Baseline levels.
| Indices | Subgroup 1 |
Subgroup 2 |
|||
|---|---|---|---|---|---|
| PD20FEV1-LTD4 ≤0.533 nmol | PD20FEV1-LTD4 >0.533 nmol | LTD4/MCh potency ratio <3,647 | LTD4/MCh potency ratio ≥3,647 | ||
| No. of patients | 18 | 5 | 13 | 10 | |
| Age (years) | 38.11±11.71 | 40.00±8.12 | 39.69±11.92 | 37.00±10.53 | |
| Height (cm) | 159.00 (11.50) | 164.20±7.26 | 161.42±6.80 | 160.65±7.66 | |
| Weight (kg) | 61.33±12.25 | 66.80±8.58 | 61.23±11.92 | 64.20±11.59 | |
| Male/female ratio | 8/10 | 3/2 | 6/7 | 5/5 | |
| Controlled (No.) | 3 | 0 | 2 | 1 | |
| Partly controlled (No.) | 5 | 1 | 3 | 3 | |
| Uncontrolled (No.) | 10 | 4 | 8 | 6 | |
| Pre-challenge FEV1 (pred%) | 91.22±14.60 | 101.12 (15.97) | 95.65±15.99 | 88.17±10.53 | |
| FeNO (ppb) | 45.50 (47.00) | 29.40±13.83 | 40.00 (52.00) | 56.70±40.70 | |
| PD20FEV1-LTD4 (nmol) | 0.25±0.12** | 0.68 (0.86) | 0.40 (0.29) | 0.20 (0.26) | |
| PD20FEV1-MCh (µmol) | 1.12±0.79** | 4.39±4.84 | 0.95±0.64** | 1.71 (3.00) | |
*P<0.05, **P<0.01 for between-group comparison; FeNO, fractional exhaled nitric oxide; FEV1, forced expiratory volume in one second; PD20FEV1-LTD4, provocative dose of LTD4 causing a 20% reduction in FEV1; PD20FEV1-MCh, provocative dose of methacholine causing a 20% reduction in FEV1.