Table 2.
Phasic and sustained anticipatory activity for the comparison of aversive to neutral trials in the 2-regressor model
| Region | Brodmann area | Size (mm3) | Center of mass (x, y, z) | Max t | Max P |
|---|---|---|---|---|---|
| Phasic anticipatory activation | |||||
| L middle/inferior occipital gyri | 18/19 | 16 952 | (−31, −82, 5) | 8.09 | 4.2E−10 |
| R middle/inferior occipital gyri | 18/19 | 15 944 | (32, −86, 6) | 7.79 | 1.1E−9 |
| L posterior cingulate gyrus | 23/31 | 5840 | (−10, −39, 31) | 3.57 | 9.1E−4 |
| L cuneus* | 17 | 4824 | (−3, −83, −1) | −5.88 | 5.9E−7 |
| R fusiform/parahippocampal gyrus | 19/37 | 2512 | (28, −52, −10) | 4.34 | 8.8E−5 |
| L orbitofrontal cortex | 11 | 896 | (−29, 45, −12) | 5.46 | 2.4E−6 |
| L anterior temporal gyrus | 38 | 736 | (−38, 25, −24) | 4.32 | 9.3E−5 |
| L middle frontal gyrus | 6 | 624 | (−39, 0, 45) | 3.95 | 2.9E−4 |
| L middle frontal gyrus | 6 | 368 | (−24, −9, 52) | 3.80 | 4.6E−4 |
| L fusiform/parahippocampal gyrus | 19/37 | 304 | (−36, −44, −12) | 3.55 | 9.6E−4 |
| L IFG/anterior insula | 47 | 280 | (−33, 29, 7) | 3.68 | 6.6E−4 |
| Sustained anticipatory activation | |||||
| R basal forebrain/BNST | N/A | 3016 | (6, −4, 1) | 4.78 | 2.2E−5 |
| Midbrain/PAG | N/A | 1856 | (−3, −28, −4) | 4.36 | 8.2E−5 |
| L anterior insula | N/A | 1768 | (−40, 20, 0) | 4.08 | 2.0E−5 |
| R anterior insula | N/A | 1752 | (34, 23, 1) | 4.58 | 4.1E−5 |
| R supramarginal gyrus | 40 | 728 | (53, −52, 32) | 3.97 | 2.8E−4 |
| L angular gyrus* | 39 | 328 | (−53, −68, 33) | −4.25 | 1.2E−4 |
*All regions showed greater activity for aversive anticipation except for the cuneus and angular gyrus, which were more active for neutral anticipation. Activation coordinates are provided in MNI space. Maximum t- and P-values are presented for illustrative purposes and are not intended as providing an independent test of significance. IFG, inferior frontal gyrus; BNST, bed nucleus of the stria terminalis; PAG, periaqueductal gray.