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. 2013 Jul;23(7):1089–1096. doi: 10.1101/gr.152710.112

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© 2013, Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 1. — (A) Outline of the data sets integrated to identify putative local adaptations (Hancock et al. 2011) and to assess the relative importance of cis-regulatory variants compared with nonsynonymous variants among these adaptations. (B) The estimated number of putative local adaptations associated with each of nine climate/geographic variables that are explicable by either a nonsynonymous SNP (green), eSNP (red), CRE SNP (blue), or combined eSNP/CRE SNP (purple). Error bars indicate the standard deviations when randomly sampling negative control SNPs (see Methods). Various controls are shown in Supplemental Figures 1–5.