Table 1.

Symptoms and classification of depression

Depressive symptoms	DSM-IV classification of depressive episode	ICD-10 classification of depressive episode
(1) Depressed mood for at least 2 weeks	Five or more symptoms, including (1) or (2)	Mild: four or more symptoms, including two of (1), (2) or (3)Moderate: six or more symptoms, including two of (1), (2) or (3)Severe: eight or more symptoms, including (1), (2) and (3)
(2) Loss of interest and enjoyment
(3) Increased fatigability
(4) Loss of confidence/self-esteema
(5) Self-reproach/guilt
(6) Suicidal thoughts or intent
(7) Reduced concentration/indecisiveness
(8) Agitation
(9) Sleep disturbance
(10) Altered appetite
Course	Single episode or recurrent	Single episode or recurrent
Additional specifiers	With/without psychotic featuresb	With/without psychotic featuresb (severe depression only)
	With/without catatonic features	With/without somatic symptoms
	With/without atypical features
	With/without postpartum onset

^aThis symptom is not outlined in DSM-IV; ^bpatients with psychotic features are generally excluded from the studies detailed in this review.

DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, 4th edition [3]; ICD-10, International Classification of Diseases, 10th revision [4].