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. Author manuscript; available in PMC: 2013 Jul 2.
Published in final edited form as: J Immunol. 2010 Apr 30;184(11):6256–6265. doi: 10.4049/jimmunol.0901463

Figure 2.

Figure 2

Serological and histological profiles at one year of age. Each symbol represents one mouse. A) ANA titers. Serum samples were screened at 1/80 and positives titrated to endpoint, B) anti-ssDNA Ab, C) anti-dsDNA Ab, D) anti-chromatin Ab and E) anti-histone Ab levels in the B6.129 congenic lines are shown. The antibody levels are expressed in arbitrary ELISA units related to a standard positive sample. F) Glomerulonephritis graded from 0 to 4 as described in Materials and Methods. Horizontal bars indicate median. The non-parametric Kruskal-Wallis test with Dunn’s multiple comparison test was applied throughout with differences being considered significant for p values <0.05. AEU = arbitrary ELISA unit