Table 2.

Hemodynamic Parameters in 8‐Week‐Old WT and HCN2‐Tg Mice

	WT	HCN2‐Tg
Blood pressure, mm Hg	103.3±2.9	104.8±2.3
Heart rate, /min	527±29.5	659±22.2*
Echocardiographic data
LVDd, mm	2.53±0.12	2.53±0.08
LVDs, mm	1.15±0.10	1.08±0.07
IVST, mm	0.73±0.02	0.68±0.02
PWT, mm	0.72±0.03	0.73±0.02
FS, %	53.8±2.0	56.7±2.8

Values are means±SEM. Numbers of mice tested are 6 for each genotype. The Mann–Whitney test was used for comparison between WT and HCN2‐Tg. WT indicates wild type; HCN2‐Tg, hyperpolarization‐activated cyclic nucleotide‐gated channel 2 transgenic mice; LVDd, left ventricular diastolic dimension; LVDs, left ventricular systolic dimension; IVST, interventricular septum thickness; PWT, posterior wall thickness; FS, fractional shortening.

^*P<0.05 vs control wild‐type littermates.