Table 4.

Relationship Between Alcohol Consumption and SCCHN within the Carolina Head and Neck Cancer Study (CHANCE) 2002–2006, Stratified by Race

	Overall							African-Americans							Whites
	Cases		Controls		Crude	Adjusted		Cases		Controls		Crude	Adjusted		Cases		Controls		Crude	Adjusted
Alcohol Use	n	%	n	%	OR	OR	95% CI	n	%	n	%	OR	OR	95% CI	n	%	n	%	OR	OR	95% CI
Total Alcohol Consumption (ml of ethanol)
Never	124	10.1	296	22.3	1	1		10	3.14	56	22	1	1		115	12.6	240	22.6	1	1
Up to 11,232	59	4.79	161	12.1	0.78	0.73	0.48, 1.11	3	0.94	29	11.4	0.62	0.47	0.09, 2.42	56	6.12	132	12.3	0.77	0.74	0.48, 1.14
11,232–204,469	234	19	406	30.6	1.32	1.19	0.86, 1.64	37	11.6	68	26.7	3.41	2.32	0.96, 5.61	197	21.5	338	31.5	1.13	1.08	0.76, 1.51
204–469–927,946	319	25.9	321	24.2	2.52	1.88	1.35, 2.61	78	24.5	62	24.3	8.49	4.71	1.97, 11.3	241	26.3	259	24.1	2.01	1.6	1.13, 2.29
927,946 and greater	496	40.2	144	10.8	9.03	4.01	2.80, 5.76	190	59.8	40	15.7	33.2	11.6	4.75, 28.4	306	33.4	104	9.69	6.71	3.17	2.13, 4.71
Likelihood Ratio Test: χ2 =12.2 df=4, P =0.02
Beers Per Week
None	243	18.4	499	36.4	1	1		38	11.1	88	33.6	1	1		205	20.9	411	37.1	1	1
<1	111	8.4	189	13.8	1.26	0.94	0.66, 1.34	12	3.5	31	11.8	0.81	0.67	0.28, 1.61	99	10.1	158	14.3	1.32	0.98	0.67, 1.43
1–4	193	14.6	295	21.5	1.42	1.13	0.83, 1.55	45	12.1	43	16.4	2.41	1.78	0.90, 3.51	148	15.1	252	22.7	1.24	1.02	0.72, 1.44
5–14	282	21.3	239	17.4	2.44	1.37	1.00, 1.89	97	28.3	62	23.7	3.29	1.66	0.91, 3.04	185	18.9	177	16	2.2	1.32	0.92, 1.88
15–29	163	12.3	72	5.3	4.68	2.16	1.46, 3.19	52	15.2	22	8.4	5.12	2.69	1.29, 5.62	111	11.3	50	4.5	4.61	2.02	1.29, 3.18
30+	331	25	77	5.6	8.77	2.85	1.96, 4.16	99	28.9	16	6.11	12.3	4.42	2.08, 9.40	232	23.7	61	5.5	7.89	2.5	1.64, 3.81
Likelihood Ratio Test: χ2 = 5.8 df=5, P =0.33
Years Drank Beer
None	243	18.6	499	36.7	1	1		38	11.2	88	33.7	1	1		205	21.2	411	37.4	1	1
<10	67	5.1	92	6.8	1.31	0.78	0.51, 1.19	14	4.1	23	8.8	1.16	0.81	0.34, 1.96	53	5.5	69	6.3	1.39	0.79	0.48, 1.28
10–19	115	8.8	134	9.9	1.44	0.97	0.57, 1.40	33	9.7	35	13.4	1.98	1.51	0.73, 3.15	82	8.5	99	9	1.33	0.85	0.56, 1.30
20+	885	67.6	636	46.7	2.79	1.67	1.27, 2.21	255	75	115	44.1	4.63	2.26	1.30, 3.95	630	65	521	47.4	2.42	1.55	1.15, 2.10
Likelihood Ra tio Test: χ2 = 2.65 df=3, P =0.45
Wines Per Week
None	634	48.2	597	43.5	1	1		110	32.5	128	48.7	1	1		524	53.7	469	42.3	1	1
<1	203	15.4	327	23.9	0.55	0.63	0.48, 0.81	15	4.42	47	17.9	0.35	0.36	0.18, 0.74	188	19.3	280	25.3	0.57	0.65	0.49, 0.86
1–4	206	15.7	284	20.7	0.59	0.62	0.47, 0.82	58	17.1	49	18.6	1.22	1.06	0.61, 1.84	148	15.2	235	21.2	0.49	0.53	0.39, 0.72
5–14	131	10	124	9	0.97	1.02	0.72, 1.43	51	15	22	8.4	2.63	1.57	0.79, 3.10	80	8.2	102	9.2	0.71	0.88	0.59, 1.29
15–29	50	3.8	28	2	1.46	0.89	0.49, 1.60	31	9.1	10	3.8	3.21	1.31	0.55, 3.15	19	2	18	1.6	0.92	0.67	0.30, 1.52
30+	91	6.9	11	8	6.08	3.42	1.71, 6.89	74	21.8	7	2.7	10.5	4.58	1.92, 11.0	17	1.7	4	0.4	3.36	2.36	0.67, 8.24
Likelihood Ratio Test: χ2 = 12.7 df=5, P =0.027
Years Drank Wine
None	634	48.9	597	44	1	1		110	32.7	128	49	1	1		524	54.6	469	42.8	1	1
<10	121	9.3	159	11.7	0.6	0.53	0.38, 0.73	40	11.9	29	11.1	1.4	1.1	0.56, 2.13	81	8.4	130	11.9	0.49	0.43	0.30, 0.62
10–19	143	11	120	8.8	0.94	1	0.72, 1.40	42	12.5	25	9.6	1.65	1.45	0.75, 2,80	101	10.5	95	8.7	0.83	0.9	0.62, 1.32
20+	398	30.7	482	35.5	0.71	0.76	0.60, 0.96	144	42.9	79	30.3	1.91	1.12	0.70, 1.78	254	26.5	403	36.7	0.55	0.68	0.42, 0.89
Likelih ood Ratio Test: χ2 = 7.35 df=3, P =0.061
Liquor Per Week
None	276	20.9	491	35.9	1	1		40	11.6	87	33.2	1	1		236	24.2	404	36.5	1	1
<1	190	14.4	276	20.2	1.09	1.24	0.91, 1.68	13	3.8	35	13.4	0.76	0.67	0.28, 1.60	177	18.2	241	21.8	1.1	1.3	0.94, 1.80
1–4	228	17.3	299	21.8	1.3	1.29	0.95, 1.75	40	11.6	51	19.5	1.84	1.57	0.78, 3.15	188	19.3	248	22.4	1.22	1.25	0.90, 1.74
5–14	205	15.5	168	12.3	2.22	1.58	1.13, 2.21	73	21.2	41	15.7	4.37	3.22	1.64, 6.34	132	13.5	127	11.5	1.82	1.26	0.87, 1.84
15–29	163	12.4	72	5.3	4.09	2.31	1.56, 3.44	50	14.5	24	9.2	5.39	3.42	1.60, 7.34	113	11.6	48	4.3	3.96	2.13	1.35, 3.34
30+	257	19.5	63	4.6	7.12	3.53	2.37, 5.26	128	37.2	24	9.2	12.6	5.75	2.83, 11.7	129	13.2	39	3.5	5.61	2.93	1.82, 4.71
Likelihood Ratio Test: χ2 = 14.1 df=5, P =0.015
Years Drank Liquor
None	276	21.1	491	36.1	1	1		87	33.2	40	11.7	1	1		236	24.5	404	36.8	1	1
<10	106	8.1	126	9.3	1.11	0.97	0.66, 1.40	26	9.9	20	5.9	1.28	1.35	0.58, 3.17	86	8.9	100	9.1	1.1	0.91	0.60, 1.37
10–19	157	12	148	10.9	1.49	1.47	1.04, 2.08	39	14.9	39	11.4	1.98	2.18	1.08, 4.42	118	12.2	109	9.9	1.47	1.36	0.93, 2.00
20+	767	58.7	594	43.7	2.22	1.83	1.39, 2.41	110	42	242	71	5.14	2.88	1.61, 5.14	525	54.4	484	44.1	1.83	1.67	1.25, 2.24
Likelihood Ratio Test: χ2 = 3.16 df=3, P =0.37

CI: confidence interval; df: degrees of freedom; OR: odds ratio

^aAll models exclude missing data. Crude models adjusted for matching factors and their interactions. Adjusted models include matching factors, their interactions, and education, fruit and vegetable consumption, duration of cigarette smoking, ever use of other tobacco products and use of other alcohol types.