Table 1.
Protein Complexes That Flip Essentiality between Schizosaccharomyces pombe and Saccharomyces cerevisiae
| Complex Name | Fraction Flipped | No. Essential in S. pombe | No. Essential in S. cerevisiae | Complex Size | Associated Lifestyle Difference |
|---|---|---|---|---|---|
| Mitochondrial ribosomal small subunit | 0.83 | 23 | 3 | 24 | Mitochondrial translation |
| Mitochondrial ribosomal large subunit | 0.85 | 36 | 2 | 40 | Mitochondrial translation |
| Clathrin | 1.00 | 2 | 0 | 2 | Golgi associated |
| GARP complex | 1.00 | 4 | 0 | 4 | Golgi associated |
| H+-transporting ATPase, Golgi | 1.00 | 11 | 0 | 11 | Golgi associated |
| Mdm12p/Mmm1p/Mdm10p complex | 1.00 | 3 | 0 | 3 | Mitochondrial translation (absence results in loss of mtDNA) |
| DASH complex | 1.00 | 0 | 9 | 9 | Spindle/Kinetochore |
| Gcd10p/Gcd14p complex | 1.00 | 0 | 2 | 2 | |
| Mtr2p/Mex67p complex | 1.00 | 0 | 2 | 2 | |
| TORC 2 complex | 1.00 | 0 | 3 | 3 | |
| Uba2p/Aos1p complex | 1.00 | 0 | 2 | 2 | |
| Anthranilate synthase complex | 1.00 | 2 | 0 | 2 | |
| SBF complex | 1.00 | 2 | 0 | 2 | |
| Ula1p/Uba3p complex | 1.00 | 2 | 0 | 2 |