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Clopidogrel pharmacokinetic and target pathway. ABCB1, ATP-binding cassette, subfamily B, member 1, encodes P-glycoprotein; CES1, carboxylesterase 1; CYPXXX, gene name and encoded proteins for the various cytochrome P450 enyzmes involved in metabolism of clopidogrel; P2RY12, purinergic receptor P2Y12; PON1, paroxonase 1. Copyright to the Pharmacogenomics Knowledge Base (PharmGKB), with permission given by PharmGKB and Stanford University to reproduce this figure.
