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Reported prevalence of CYP2C9 and VKORC1 gene polymorphisms by ancestry (Limdi et al., 2008a,b; Cavallari et al., 2010; Limdi et al., 2010; Chan et al., 2012a)
| Allele | Prevalence* |
||
|---|---|---|---|
| European | African | Asian | |
| % | |||
| CYP2C9*2 (R144C) | 24 | 3-4 | <1 |
| CYP2C9*3 (I359L) | 12 | 1-3 | 6-8 |
| CYP2C9*5 (D360E) | <1 | 1-2 | <1 |
| CYP2C9*6 (10601delA) | <1 | 1 | <1 |
| CYP2C9*8 (R150H) | NR | 12 | <1 |
| CYP2C9*11 (R335W) | <1 | 3 | <1 |
| VKORC1 -1639G>A | 61 | 20 | 99 |
| CYP4F2 V433M | 40 | 14 | 40–42 |
Percentage of individuals who have the variant.
