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. 2013 Jul;65(3):987–1009. doi: 10.1124/pr.112.007252

TABLE 5.

Recommended warfarin starting dose in mg/day according to VKORC1 and CYP2C9 genotypes per the FDA-approved warfarin labeling

VKORC1 -1639 CYP2C9
*1/*1 *1/*2 *1/*3 or *2/*2 *2/*3 *3/*3
GG 5–7 5–7 3–4 3–4 0.5–2
AG 5–7 3–4 3–4 0.5–2 0.5–2
AA 3–4 3–4 0.5–2 0.5–2 0.5–2