Table 1.

Baseline respiratory and metabolic measurements

	A/J	B6a1	B6	B6 with saline	B6 with Buspirone
f, breaths/min	205.7 ± 10.8	204.2 ± 15.7	199.1 ± 22.9	209.8 ± 21.3	286.5 ± 20.1 §§
VT /body wt, µl • g−1	1.38 ± 0.18	1.24 ± 0.19	1.20 ± 0.15	1.29 ± 0.22	1.60 ± 0.21 §
V̇E / body wt, ml • min−1 • g−1	0.29 ± 0.04	0.25 ± 0.05	0.24 ± 0.02	0.27 ± 0.06	0.46 ± 0.09 §§
V̇O2 / body wt, ml • min−1 • g−1 • 10−2	8.54 ± 0.77	7.74 ± 0.91	9.58 ± 0.84 ††	9.74 ± 0.97	11.21 ± 0.97
V̇CO2 / body wt, ml • min−1 • g−1 • 10−2	4.49 ± 0.60	4.48 ± 0.25	5.64 ± 0.60 ††**	5.94 ± 0.86	7.08 ± 0.77
Body Temperature, °C	36.0 ± 0.4	35.7 ± 0.1	36.5 ± 0.1 ††*	36.5 ± 0.2	36.3 ± 0.4
Body weight, g	25.2 ± 1.7	26.6 ± 2.1	26.1 ± 1.8	26.6 ± 1.8	26.5 ± 2.2
RQ	0.52 ± 0.04	0.58 ± 0.05	0.59 ± 0.04 *	0.61 ± 0.09	0.63 ± 0.04
V̇E / V̇O2	3.34 ± 0.43	3.30 ± 0.58	2.48 ± 0.20 †*	2.78 ± 0.56	4.10 ± 0.58 §§
V̇E / V̇CO2	6.41 ± 1.08	5.66 ± 0.93	4.23 ± 0.43 †**	4.65 ± 1.17	6.51 ± 0.83

Values are mean ± SD, One-Way ANOVA was performed to detect strain differences (A/J, B6a1, and B6). Paired t-tests were performed to evaluate the effect of buspirone.

^*Significant differences from A/Js (*<0.05, ** <0.01).

^†Significant differences from B6a1s (†<0.05, ††<0.01).

^§Significant difference from saline treated animals (§<0.05, §§ <0.01)