Table 2.
Cost, resource utilization, and market share data from nine European countries used to populate the economic model
Austria | Belgium | Czech Republic | Hungary | Italy | Latvia | The Netherlands | Poland | Portugal | |
---|---|---|---|---|---|---|---|---|---|
Costs (€) | |||||||||
Eligard® 1 M (7.5 mg) | 106.80 | 95.70 | 121.60 | 100.39 | 149.77 | 111.66 | 106.80* | 81.78 | 148.20 |
Eligard® 3 M (22.5 mg) | 320.40 | 194.52 | 314.95 | 280.55 | 387.49 | 319.03 | 320.40 | 240.57 | 399.41 |
Eligard® 6 M (45 mg) | 619.22 | 320.06 | 629.93** | 558.11 | 774.98 | 466.87 | 619.22 | 481.14 | 779.66 |
Urologist consultation§ | 29.42 | 28.56 | 4.23 | 2.42 | 20.70 | 38.96 | 86.00 | 8.65 | 35.43 |
PSA test | 11.10 | 10.78 | 14.46 | 4.75 | 19.10 | 7.14 | 27.65 | 7.21 | 8.14 |
Ultrasound scan | 27.66 | 37.37 | 12.10 | 1.80 | 43.40 | 12.99 | 85.00 | 7.21 | 43.16 |
Adverse events# | 21.80 | 18.24 | 4.23 | 1.79 | 20.70 | 16.88 | 86.00 | 3.85 | 35.43 |
Nonmedical cost per visit‡ | 5.70 | 4.40 | 3.57 | 5.22 | 4.00 | 10.39 | 7.00 | 2.16 | 4.20 |
Indirect cost per visit|| | 23.81 | 33.70 | 6.80 | 6.25 | 28.57 | 6.18 | 33.91 | 7.93 | 11.55 |
Resource utilization (%) – diagnostic visits | |||||||||
Monthly | 0.24 | 0.24 | 0.90 | 0.88 | 0.90 | 0.90 | 0.24 | 0.90 | 0.90 |
3-monthly | 4.75 | 4.75 | 9.00 | 8.77 | 9.00 | 9.00 | 4.75 | 9.00 | 9.00 |
Estimated market share (%) | |||||||||
Eligard® 1 M | 20.0 | 30.0 | 10.4 | 32.0 | 10.0 | 15.0 | 0 | 2.2 | 8.0 |
Eligard® 3 M | 60.0 | 70.0 | 90.6 | 68.0 | 87.0 | 80.0 | 20.2 | 65.8 | 90.0 |
Notes:
1 M formulation was not marketed and its unit cost was assumed to be one-third of the 3 M formulation;
monthly cost assumed to be equivalent to that of 3 M and was varied in the sensitivity analysis;
doctor, nurse, and injection costs;
GP/urologist consultation;
public transport;
productivity loss based on minimum wage and accounting for retirement status. Registered trademarks of Eligard®, Sanofi S.A./Tolmar Therapeutics Inc (Fort Collins, CO, USA).
Abbreviations: 1 M, 1-monthly; 3 M, 3-monthly; 6 M, 6-monthly; PSA, prostate-specific antigen; GP, general practitioner.