Table 6.

Relative expression (treatment means, log-2 scale) of genes encoding transcription regulators, nuclear receptor co-activators and co-repressors during the peripartal period in cows fed (n = 5/treatment) control, fish oil (FISH), or saturated lipid (SFAT).

Gene	Prepartum			Postpartum			SEM†	P value
	Control	FISH	SFAT	Control	FISH	SFAT		Diet	Time	D × T‡
Transcription regulators
PPARA	0.41	0.63	0.26	0.38	0.49	0.14	0.23	0.54	0.31	0.88
RXRA	3.17	2.85	2.31	2.60	1.36	2.24	0.57	0.30	0.06	0.77
PPARD	3.18	2.86*	1.93	3.72a	1.19b,*	2.22b	0.45	0.04	0.18	<0.01
SREBF2	4.43a	3.74a,b,*	3.18b	3.72a	2.59b,*	3.74a	0.36	0.01	0.66	0.02
Nuclear receptor co-activators
CARM1	4.20a	3.48b,*	2.84b	4.04a	2.10b,*	3.24a,b	0.37	0.03	0.08	<0.01
MED1	4.30a	3.57b,*	2.89b	4.21a	2.15c,*	3.37b	0.38	0.02	0.12	<0.01
Nuclear receptor co-repressors
NCOR2	3.67a	3.00a,b,*	2.35b	3.69a	1.91b,*	2.73b	0.33	0.01	0.30	0.04
NRIP1	3.60a	2.78b,*	2.40b	3.48a	1.64b,*	2.72b	0.36	0.03	0.14	0.03

Notes:

^†Standard error of the mean;

^‡diet × time interaction.

^a–cDifference (D × T, P < 0.05) between diets at the prepartum or postpartum times.

^*Difference (D × T, P < 0.05) prepartum vs. postpartum within diet.