Table 4.
Comparison of mean ICSI total scores between chondroitin sulphate and control groups at end of treatment period and end of study
| Study | End of treatment | End of study | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Condroitin sulphate | Control | Difference | Condroitin sulphate | Control | Difference | |||||
|
| ||||||||||
| n | R | n | R | (95% CI) | n | R | n | R | (95% CI) | |
| ICSI after treatments | ||||||||||
|
| ||||||||||
| RCT 1 | 33 | 11.0 (4.8) | 31 | 11.9 (3.8) | −0.9 (−3.1, 1.2) | 29 | 11.1 (5.0) | 30 | 11.5 (4.5) | −0.4 (−2.9, 2.06) |
| RCT 2 | 50 | 9.7 (5.0) | 48 | 9.7 (4.9) | 0.0 (−2.0, 2.0) | 44 | 10.6 (5.1) | 44 | 9.4 (4.3) | 1.2 (−0.8, 3.1) |
| OLS | 53 | 9.2 (4.2) | – | – | – | 53 | 8.3 (5.0) | – | – | – |
| Pooled (95% CI) | −0.8 (−4.0, 2.4)* | 0.5 (−5.8, 4.8)** | ||||||||
*
p = 0.404;
**
p = 0.743. ICSI: Interstitial Cystitis Symptom Index; CI: confidence interval; RCT: randomized control trial; OLS: open-label study.