Table 2.

Color difference in rat skin treated with microemulsions containing different amounts of citalopram at different time points as measured by colorimetry

	Control	2 hours		6 hours
		Citalopram 0%	Citalopram 3%	Citalopram 0%	Citalopram 3%
L*	66.96 ± 2.32	62.95 ± 2.06	68.72 ± 0.95	62.40 ± 0.80	67.62 ± 0.94
a*	4.65 ± 0.88	7.87 ± 2.74	5.44 ± 0.85	8.56 ± 1.93	6.65 ± 1.92
b*	1.62 ± 1.53	2.31 ± 0.36	−1.74 ± 1.03	1.35 ± 0.64	−2.27 ± 0.56

Notes: Control, untreated rat skin site. L*, white-black index; a*, red-green index; b*, yellow-blue index. All four groups of formulations showed no significant difference in L* (white-black index) or a* (red-green index) compared with untreated skin near attachment site. All data represent the mean of three experiments.