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Effects of methotrexate and anti-TNFα treatment on peripheral B cell subpopulations. Comparative frequencies of CD19+CD10+IgMhiCD27− new emigrant B cell, CD19+CD10−IgM+CD27− mature naïve B cells and CD19+CD10−CD27+ memory B cells from RA patients before and after methotrexate and anti-TNFα therapies. Each symbol represents an individual and the average is shown with a dashed bar.
