Table 3. Summary of Ages of Onset of Electrocardiographic Characteristics.

All data are shown as n; mean ± SD (range)	Mutation Positive n=64	Mutation negative n=39	P-value
Age with first available ECG data when accompanied by LVE, systolic dysfunction or both	8; 44.1 ± 11.2 (28-62)	0	n/a
Age at first abnormal ECG	51; 42.1 ± 11.0 (18-76)	8; 40.4 ± 16.4 (18-62)	0.7844
Age at ≥2 ECG abnormalities with first available data	13; 46.1 ± 11.5 (31-62)	2; 48.5 ± 17.7 (36-61)	0.7822
Age of onset of ECG abnormality with normal ventricular size and function that progressed to DCM	16; 43.0 ± 9.7 (28-62)	0	n/a
Ages of detection of sinoatrial findings	35; 42.9 ± 8.9 (27-62)	3; 51.0 ± 8.7 (45-61)	0.2920
Atrioventricular conduction block (1-3)	27; 41.1 ± 7.9 (27-63)	3; 51.0 ± 8.7 (45-61)	0.2260
Sinus node dysfunction	6; 50.2 ± 9.5 (39-62)	0	n/a
Placement of Permanent Pacemaker	27; 46.2 ± 8.9 (31-69)	1; 62
Ages with sinoatrial findings only at presentation	15; 39.8 ± 8.0 (27-58)	2; 46.0 ± 1.4 (45-47)	0.0198
Ages at detection of any arrhythmia	41; 45.1 ± 11.3 (25-76)	6; 41.7 ± 19.7 (18-64)	0.6812
Atrial fibrillation/flutter	24; 47.0 ± 9.2 (31-65)	2; 56.0 ± 11.3 (48-64)	0.1174
Supraventricular tachycardia	4; 35.8 ± 9.7 (25-49)	3; 40.7 ± 17.8 (22-64)	0.6904
Premature atrial or ventricular contractions	22; 45.96 ± 14.5 (27-82)	4; 43.5 ± 31.1 (18-62)	0.9142
Ventricular tachycardia/fibrillation	9; 55.2 ± 12.8 (40-82)	1; 72	n/a
Implantable cardioverter-defibrillator	9; 44.3 ± 8.2 (33-61)	0	n/a
Sudden cardiac death	1; 42	0	n/a
Ages with arrhythmia only at presentation	15; 41.7 ± 8.8 (25-62)	2; 20.0 ± 2.8 (18-22)	0.0028
Ages of detection of His/bundle dysfunction	14; 43.6 ± 14.4 (18-76)	4; 47.8 ± 16.0 (32-62)	0.6784
Right bundle branch block	2; 34.0 ± 19.8 (20-48)	4; 47.8 ± 16.0 (32-62)	0.4512
Left bundle branch block	6; 49.2 ± 14.5 (37-76)	0	n/a
Non-specific or not otherwise specified IVCD	6; 41.3 ± 13.0 (18-54)	0	n/a
Ages of His/bundle dysfunction only at presentation	4; 32.0 ± 15.2 (18-48)	1; 32	n/a