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. Author manuscript; available in PMC: 2013 Aug 6.
Published in final edited form as: Sci Transl Med. 2013 Feb 6;5(171):171ra19. doi: 10.1126/scitranslmed.3004794

Fig. 1. Antibody isotype distribution changes after vaccination.

Fig. 1

(A), antibody isotype composition in PBMCs at visit 1 (before vaccination, top) and visit 3 (28 ± 4 days after vaccination, bottom) averaged for all subjects. (B), percent change of individual’s relative IgM usage in PBMCs from visit 1 to visit 3. The subject IDs were labeled on horizontal axis. (C), comparison of relative change in IgM in different age group and vaccine types. p value was calculated by Mann-Whitney U test (3 samples for TIV receivers of age 8-17, 5 samples for TIV receivers of age 18-32, 4 samples for TIV receivers of age 70-100, 3 samples for LAIV receivers of age 8-17 and 2 samples for LAIV receivers of age 18-32). Red, LAIV receivers; blue, TIV receirvers. Percent change = (IgM reads in visit 1/total reads in visit 1) – (IgM reads in visit 3/total reads in visit 3)

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