Table 4.

Sensitivity analysis: exposure to PPIs and risk of hospitalisation for pneumonia; self- controlled case-series adjusted analysis in patients alive at discharge

Risk periods	Number of hospitalizations for pneumonia	Person-years	Adjusted* rate ratios (95% CI)
Baseline unexposed to a proton pump inhibitor
Unexposed	4680	16676	1.0
Pre-exposure to a proton pump inhibitor
Pre 1–30 days	438	347	5.71 (5.37 – 6.07)
Pre 31–60 days	161	319	2.30 (2.11 – 2.51)
Pre 61–120 days	141	530	1.21 (1.11 – 1.33)
Post-exposure to proton pump inhibitors
1–7 days	52	81	2.87 (2.49 – 3.32)
8–30 days	112	262	1.95 (1.76 – 2.16)
>30 days	944	2786	1.55 (1.46 – 1.65)

* Adjusted for time-varying age and study year only.