Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dose reduction indexes (DRIs) for doxycycline (MyD88 inhibition) and chemotherapy agents upon combination of the two in HCT116 p53+/+ or p53–/– cells expressing a doxycycline-inducible MyD88 short hairpin RNA (shMyD88) in vitro
| Treatment | DRI | |||
|---|---|---|---|---|
| Doxycycline | Chemotherapy | Doxycycline | Chemotherapy | |
| Doxycyclin–cisplatin | 7.4 | 2.4 | 3.8 | 14.4 |
| Doxycyclin–oxaliplatin | 4.4 | 8.2 | 2.3 | 2.7 |
