Table 6. Detection of Gram positive identification and resistance determinants from contrived blood cultures by Verigene BC-GP (n = 387).
| Target | TP | FP | TN | FN | Totala | Sensitivity (CI)b | Specificity (CI) |
| Identification | |||||||
| Staphylococcus spp. | 54 | 1 | 332 | 0 | 387 | 100% (93–100) | 99.7% (98–100) |
| S. aureus | 10 | 0 | 377 | 0 | 387 | 100% (69–100) | 100% (99–100) |
| S. epidermidis | 4 | 0 | 383 | 0 | 387 | 100% (39–100) | 100% (99–100) |
| S. lugdunensis | 31 | 1 | 355 | 0 | 387 | 100% (88–100) | 99.7% (98–100) |
| Streptococcus spp. | 154 | 1 | 231 | 1 | 387 | 99.3% (69–100) | 99.6% (97–100) |
| S. pyogenes | 66 | 0 | 319 | 2 | 387 | 97.1% (97–99) | 100% (98–100) |
| S. agalactiae | 36 | 0 | 351 | 0 | 387 | 100% (90–100) | 100% (98–100) |
| S. anginosus gr. | 26 | 1 | 360 | 0 | 387 | 100% (86–100) | 99.7% (98–100) |
| S. pneumoniae | 21 | 0 | 366 | 0 | 387 | 100% (83–100) | 100% (99–100) |
| E. faecalis | 32 | 0 | 354 | 1 | 387 | 97.0% (84–99) | 100% (98–100) |
| E. faecium | 77 | 1 | 309 | 0 | 387 | 100% (95–100) | 99.7% (98–100) |
| Listeria | 33 | 0 | 354 | 0 | 387 | 100% (89–100) | 100% (98–100) |
| Resistance | |||||||
| mecA c | 9 | 0 | 5 | 0 | 14 | 100% (66–100) | 100% (47–100) |
| vanA d | 45 | 3 | 62 | 0 | 110 | 100% (92–100) | 95.4% (87–99) |
| vanB d | 39 | 0 | 70 | 1 | 110 | 97.5% (89–99) | 100% (94–100) |
a
Total number of cultures with reported result.
b
95% confidence interval.
c
mecA is reported only for cultures with positive S. aureus or S. epidermidis species targets.
d
vanA and vanB are reported only for cultures with positive E. feacium or E. faecalis targets.
FN, false negative; FP, false positive; TN, true negative; TP, true positive.