TABLE 1.
Gestation Day | Virgin | gd8 | gd10 | gd12 | gd14 | gd16 | Overall | |
---|---|---|---|---|---|---|---|---|
Body weight (g) | Control | 26.9±1.4 | 26.8±0.6 | 27.7±0.7 | 28.7±1.8 | 29.8±1.5 | 33.4±2.0 | |
Diabetic | 23.5±0.2 | 24.5±1.4 | 27.1±2.5 | 30.4±1.2 | 29.2±1.4 | 31.1±0.9 | ||
p value | NS | NS | NS | NS | NS | NS | NS | |
Initial Blood Glucose (mmol/L) | Control | 6.4±0.6 | 5.5±0.3 | 5.9±0.3 | 4.9±0.4 | 5.5±0.5 | ||
Diabetic | 26.3±4.2 | 19±1.9 | 24.9±2.1 | 21.3±1.2 | 21.8±1.5 | |||
p value | 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | ||
Final Blood Glucose (mmol/L) | Control | 6.3±0.6 | 8.7±0.4 | 8±0.4 | 7.8±1.1 | 6±0.5 | 6.3±0.6 | |
Diabetic | 28.6±0.9 | 30.2±1.3 | 30.0±1.9 | 27.7±2.8 | 31.4±1.0 | 31.0±2.3 | ||
p value | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | |
Viable Litter Size | Control | 10.7±0.9 | 11.3±0.3 | 7.7±1.3 | 8±1.2 | 5.7±0.9 | ||
Diabetic | 11±0 | 8.3±1.8 | 8.7±1.9 | 8.7±0.9 | 6.7±2.9 | |||
p value | NS | NS | NS | NS | NS | NS | ||
Maternal Heart Rate (BPM) | Control | 433.2±15.8 | 442.9±13.5 | 422.2±26.4 | 449.5±7.3 | 479.4±21.8 | 486.9±2.3 | |
Diabetic | 425.3±22.3 | 449.8±6.7 | 427.1±8.9 | 407.0±1.6 | 402.5±18.0 | 380.3±44.3 | ||
p value | NS | NS | NS | NS | NS | 0.006 | 0.005 |
Significant differences between groups overall and at each individual time-point were determined by two-way ANOVA with Bonferroni’s post-test.