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. 2013 Jul 2;8(7):e68743. doi: 10.1371/journal.pone.0068743

Figure 3. Canonical myostatin signaling following resistance exercise.

Figure 3

The expression of genes within the myostatin pathway was determined in TA muscle at the end of a 20 min bout of high force lengthening contractions and then 0.5, 3, 6, 18, and 48 hours later. Myostatin and follistatin mRNA increased following resistance exercise starting at 3 h. The expression of the myostatin receptor (ActRIIB) was unchanged at any time point. *indicates significantly greater than the contralateral control leg for follistatin and † indicates significantly greater than the contralateral control leg for myostatin (n = 4, p<0.05).