Skip to main content
. 2013 Jul 2;8(7):e65629. doi: 10.1371/journal.pone.0065629

Figure 3. Immunohistochemical localisation of CA8, SLC4A1 and CLIC3 gene products in embryonic (E15) and adult lateral choroid plexus.

Figure 3

Embryonic choroid plexus (A, C, E) is compared to that of adult (B, D, F). Note the differences in patterns of immunoreactivity between the ages. Embryonic plexus epithelium is strongly stained for CA8 while virtually no reactivity was detected in the vasculature (A). Adult plexus is unstained (B). SLC4A1 immunoreactivity is pronounced in E15 plexus where all cell nuclei and cytoplasm in both epithelium and endothelium are strongly positive (C), whereas the immunoreactivity in the adult plexus is varying but mainly nuclear in both epi- and endothelium (D). Following staining for CLIC3 a marked reaction is observed in the entire embryonic plexus (E) in contrast to that in the adult where vasculature is devoid of staining and the cytoplasm of scattered choroid plexus epithelial cells is strongly immunoreactive (F). Scale bars: 100 µm for all. Abbreviation: CSF, cerebrospinal fluid.