Table 2. Clinical characteristics of non-sepsis obstetric population compared to women with uncomplicated sepsis, compared to severe sepsis, compared to septic shock in California (2005–2007).
Obstetric population without sepsis | P-value* | Uncomplicated sepsis | P-value* | Severe sepsis | P-value* | Septic shock | |
n = 1620876 | n = 807 | n = 735 | n = 56 | ||||
Prenatal care | 0.13 | 0.593 | 0.292 | ||||
Adequate | 1299448 (80.2) | 630 (78.1) | 582 (79.2) | 41 (73.2) | |||
Inadequate | 321428 (19.8) | 177 (21.9) | 153 (20.8) | 15 (26.8) | |||
Parity | 0.216 | <0.0001 | 0.575 | ||||
Primiparous | 625377 (38.6) | 293 (36.5) | 349 (47.6) | 24 (43.6) | |||
Multiparous | 994185 (61.4) | 510 (63.5) | 385 (52.4) | 31 (56.4) | |||
Multiple pregnancy | 0.626 | <0.0001 | 0.66 | ||||
Singleton | 1571423 (96.9) | 780 (96.7) | 657 (89.4) | 49 (87.5) | |||
Multiple | 49453 (3.1) | 27 (3.4) | 78 (10.6) | 7 (12.5) | |||
Chronic Co-Morbidities | |||||||
Diabetes | 113014 (7.0) | 0.014 | 74 (9.2) | <0.0001 | 112 (15.2) | 0.381 | 11 (19.6) |
Chronic hypertension | 15850 (1.0) | 0.266 | 11 (1.4) | <0.0001 | 37 (5.0) | 1.00 | 2 (3.6) |
Mode of delivery | <0.0001 | 0.001 | 0.006 | ||||
Spontaneous vaginal | 1037472 (64.0) | 425 (52.7) | 314 (42.7) | 17 (30.4) | |||
Primary caesarean | 292114 (18.0) | 232 (28.8) | 272 (37.0) | 34 (60.7) | |||
Repeat caesarean | 216915 (13.4) | 120 (14.9) | 123 (16.7) | 4 (7.1) | |||
Operative vaginal** | 74375 (4.6) | 30 (3.7) | 26 (3.5) | 1 (1.8) | |||
BMI (2007 only) | n = 481994 | n = 250 | n = 211 | n = 17 | |||
Median (IQR) | 24.3 (21.5–28.3) | 0.642*** | 24.5 (21.8–28.7) | 0.298*** | 25.6 (22.1–29.3) | 0.379*** | 24.2 (19.4–29.2) |
Figures are numbers (%) of women.
Difference in distribution between groups; χ2 test; Fisher's exact test for <5 observations.
Forceps or vacuum extraction.
Wilcoxon rank-sum (Mann-Whitney) test.